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A Multifaceted Disease

With one foot in Asia and the other in Europe,

advances in Russian ophthalmology shouldn’t go unnoticed by the rest of the world.

 In this session on Day 3 of the World Glaucoma e-Congress (WGC 2021), four experts bring us up to speed on glaucoma research in Russia.

Neuroimaging the brain of glaucoma patients To begin, Dr. Ilmira Gazivova, from the Federal Budgetary Institution of Science (Russia) ลาวสามัคคี วีไอพี

discussed neuroimages of the brain in glaucoma studies.

 Dr. Gazivova shared: “We know that glaucoma affects more than just the brain’s visual pathways, which means that we can scan the brain for it in the same way as other neurodegenerative diseases.

 We know that patients with POAG are up to five times more likely to suffer from other neurodegenerative diseases such as Alzheimer’s and Parkinson’s than others.”

Qualitative analysis suggests that glucose metabolism in the neurons of patients with POAG indicate an affinity with other neurodegenerative diseases.

This suggests that the basis of visual, cognitive,

autonomic disorders associated with changes

in function of the central nervous system may well be the same as that of patients with POAG, and therefore more research in this direction should be continued.

The effect of pseudoexfoliation syndrome on glaucoma Dr. Andrey Brezhnev from Kursk State Medical University (Russia)

discussed pseudoexfoliation syndrome (PXS): from genetics to glaucoma surgery.

PXS is an age-related generalized disorder of the extracellular matrix, characterized by excessive production and progressive accumulation of a fibrillar extracellular material in extraocular tissues.

 It has a related form of glaucoma called pseudoexfoliation glaucoma (PXG) which is 20x more prevalent in PXS patients than glaucoma is in the general public.

PXS is widespread in the population of Central Russia and is a complex, multifactorial disease that includes a combination of genetic and non-genetic factors.

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